Details

Top
Internal ID 44d2dc60-4e9d-41ea-b416-9cf8507ae7e7
Taxonomy Organic acids and derivatives > Peptidomimetics > Depsipeptides > Cyclic depsipeptides
IUPAC Name
SMILES (Canonical) CC1C(C(=O)N(C(C(=O)NC(C(=O)N2CCCC2C(=O)NC(C(=O)O1)CC(=O)O)C(C)C)CCC(=O)N)C)NC(=O)C(CS(=O)(=O)O)NC(=O)C(CCCNC(=N)N)NC(=O)C(CC3=CNC4=CC=CC=C43)NC(=O)C(C(C)(C)C)NC(=O)C(C(C)C)NC(=O)C5CCCN5C(=O)C(CC6=CC=C(C=C6)Br)NC(=O)C(C)NC=O
SMILES (Isomeric) C[C@@H]1[C@@H](C(=O)N([C@H](C(=O)N[C@@H](C(=O)N2CCC[C@H]2C(=O)N[C@@H](C(=O)O1)CC(=O)O)C(C)C)CCC(=O)N)C)NC(=O)[C@@H](CS(=O)(=O)O)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@@H](CC3=CNC4=CC=CC=C43)NC(=O)[C@H](C(C)(C)C)NC(=O)[C@@H](C(C)C)NC(=O)[C@@H]5CCCN5C(=O)[C@H](CC6=CC=C(C=C6)Br)NC(=O)[C@@H](C)NC=O
InChI InChI=1S/C73H105BrN18O21S/c1-36(2)55(86-65(103)52-20-14-28-91(52)68(106)47(83-59(97)38(5)80-35-93)30-40-21-23-42(74)24-22-40)66(104)89-58(73(7,8)9)67(105)82-46(31-41-33-79-44-17-12-11-16-43(41)44)61(99)81-45(18-13-27-78-72(76)77)60(98)85-49(34-114(110,111)112)62(100)88-57-39(6)113-71(109)48(32-54(95)96)84-64(102)51-19-15-29-92(51)70(108)56(37(3)4)87-63(101)50(25-26-53(75)94)90(10)69(57)107/h11-12,16-17,21-24,33,35-39,45-52,55-58,79H,13-15,18-20,25-32,34H2,1-10H3,(H2,75,94)(H,80,93)(H,81,99)(H,82,105)(H,83,97)(H,84,102)(H,85,98)(H,86,103)(H,87,101)(H,88,100)(H,89,104)(H,95,96)(H4,76,77,78)(H,110,111,112)/t38-,39-,45+,46-,47+,48-,49-,50+,51+,52+,55-,56-,57+,58-/m1/s1
InChI Key JYQSNSNXXDQETE-PARQPDGVSA-N
Popularity 0 references in papers

Physical and Chemical Properties

Top
Molecular Formula C73H105BrN18O21S
Molecular Weight 1682.70 g/mol
Exact Mass 1680.66058 g/mol
Topological Polar Surface Area (TPSA) 599.00 Ų
XlogP 0.40

Synonyms

Top
There are no found synonyms.

2D Structure

Top
2D Structure of

3D Structure

Top

ADMET Properties (via admetSAR 2)

Top
Target Value Probability (raw) Probability (%)
No predicted properties yet!

Targets

Top

Proven Targets:

CHEMBL ID UniProt ID Name Min activity Assay type Source
No proven targets yet!

Predicted Targets (via Super-PRED):

CHEMBL ID UniProt ID Name Probability Model accuracy
CHEMBL2581 P07339 Cathepsin D 99.96% 98.95%
CHEMBL333 P08253 Matrix metalloproteinase-2 99.94% 96.31%
CHEMBL1795139 Q8IU80 Transmembrane protease serine 6 99.81% 98.33%
CHEMBL5103 Q969S8 Histone deacetylase 10 99.45% 90.08%
CHEMBL3837 P07711 Cathepsin L 99.34% 96.61%
CHEMBL2693 Q9UIQ6 Cystinyl aminopeptidase 99.33% 97.64%
CHEMBL3108638 O15164 Transcription intermediary factor 1-alpha 99.16% 95.56%
CHEMBL3251 P19838 Nuclear factor NF-kappa-B p105 subunit 98.65% 96.09%
CHEMBL2069156 Q14145 Kelch-like ECH-associated protein 1 98.61% 82.38%
CHEMBL5619 P27695 DNA-(apurinic or apyrimidinic site) lyase 98.39% 91.11%
CHEMBL3729 P22748 Carbonic anhydrase IV 98.26% 99.23%
CHEMBL4588 P22894 Matrix metalloproteinase 8 98.26% 94.66%
CHEMBL5043 Q6P179 Endoplasmic reticulum aminopeptidase 2 98.13% 91.81%
CHEMBL261 P00915 Carbonic anhydrase I 97.98% 96.76%
CHEMBL4123 P30989 Neurotensin receptor 1 97.77% 96.67%
CHEMBL321 P14780 Matrix metalloproteinase 9 97.64% 92.12%
CHEMBL4801 P29466 Caspase-1 97.13% 96.85%
CHEMBL2514 O95665 Neurotensin receptor 2 97.07% 100.00%
CHEMBL3524 P56524 Histone deacetylase 4 96.82% 92.97%
CHEMBL2492 P36544 Neuronal acetylcholine receptor protein alpha-7 subunit 96.70% 88.42%
CHEMBL5852 Q96P65 Pyroglutamylated RFamide peptide receptor 96.67% 85.00%
CHEMBL1937 Q92769 Histone deacetylase 2 95.76% 94.75%
CHEMBL5163 Q9NY46 Sodium channel protein type III alpha subunit 95.41% 96.90%
CHEMBL4777 P25929 Neuropeptide Y receptor type 1 95.28% 96.67%
CHEMBL1907594 P30926 Neuronal acetylcholine receptor; alpha3/beta4 95.10% 97.23%
CHEMBL1163125 O60885 Bromodomain-containing protein 4 95.05% 97.31%
CHEMBL1293287 P14735 Insulin-degrading enzyme 95.03% 88.10%
CHEMBL3137262 O60341 LSD1/CoREST complex 95.00% 97.09%
CHEMBL3392948 Q9NP59 Solute carrier family 40 member 1 94.89% 95.00%
CHEMBL3130 O00329 PI3-kinase p110-delta subunit 94.84% 96.47%
CHEMBL4979 P13866 Sodium/glucose cotransporter 1 94.74% 98.24%
CHEMBL3807 P17706 T-cell protein-tyrosine phosphatase 94.71% 93.00%
CHEMBL3310 Q96DB2 Histone deacetylase 11 94.21% 88.56%
CHEMBL5608 Q16288 NT-3 growth factor receptor 93.63% 95.89%
CHEMBL5966 P55899 IgG receptor FcRn large subunit p51 93.58% 90.93%
CHEMBL1914 P06276 Butyrylcholinesterase 93.42% 95.00%
CHEMBL3038477 P67870 Casein kinase II alpha/beta 93.39% 99.23%
CHEMBL4227 P25090 Lipoxin A4 receptor 93.38% 100.00%
CHEMBL205 P00918 Carbonic anhydrase II 93.31% 98.44%
CHEMBL259 P32245 Melanocortin receptor 4 92.59% 95.38%
CHEMBL5028 O14672 ADAM10 92.40% 97.50%
CHEMBL1806 P11388 DNA topoisomerase II alpha 91.81% 89.00%
CHEMBL2179 P04062 Beta-glucocerebrosidase 91.78% 85.31%
CHEMBL4478 Q00975 Voltage-gated N-type calcium channel alpha-1B subunit 91.40% 97.14%
CHEMBL4394 Q9NYA1 Sphingosine kinase 1 90.73% 96.03%
CHEMBL4644 P41968 Melanocortin receptor 3 89.91% 99.52%
CHEMBL340 P08684 Cytochrome P450 3A4 89.45% 91.19%
CHEMBL1907591 P30926 Neuronal acetylcholine receptor; alpha4/beta4 89.39% 100.00%
CHEMBL4018 P49146 Neuropeptide Y receptor type 2 89.35% 98.94%
CHEMBL3359 P21462 Formyl peptide receptor 1 89.25% 93.56%
CHEMBL4393 P39900 Matrix metalloproteinase 12 89.19% 92.22%
CHEMBL4073 P09237 Matrix metalloproteinase 7 89.02% 97.56%
CHEMBL4296 Q15858 Sodium channel protein type IX alpha subunit 89.00% 96.11%
CHEMBL1744525 P43490 Nicotinamide phosphoribosyltransferase 88.98% 96.25%
CHEMBL2094135 Q96BI3 Gamma-secretase 88.48% 98.05%
CHEMBL3230 O95977 Sphingosine 1-phosphate receptor Edg-6 88.34% 94.01%
CHEMBL1907600 Q00535 Cyclin-dependent kinase 5/CDK5 activator 1 87.82% 93.03%
CHEMBL3060 Q9Y345 Glycine transporter 2 86.62% 99.17%
CHEMBL2803 P43403 Tyrosine-protein kinase ZAP-70 86.39% 82.50%
CHEMBL4026 P40763 Signal transducer and activator of transcription 3 86.17% 82.69%
CHEMBL2535 P11166 Glucose transporter 84.65% 98.75%
CHEMBL5939 Q9NZ08 Endoplasmic reticulum aminopeptidase 1 84.59% 100.00%
CHEMBL4816 Q9Y243 Serine/threonine-protein kinase AKT3 84.23% 96.28%
CHEMBL1900 P15121 Aldose reductase 83.76% 92.38%
CHEMBL217 P14416 Dopamine D2 receptor 83.56% 95.62%
CHEMBL3476 O15111 Inhibitor of nuclear factor kappa B kinase alpha subunit 83.39% 95.83%
CHEMBL2072 P35499 Sodium channel protein type IV alpha subunit 83.19% 92.32%
CHEMBL4203 Q9HAZ1 Dual specificity protein kinase CLK4 82.50% 94.45%
CHEMBL3594 Q16790 Carbonic anhydrase IX 82.39% 99.23%
CHEMBL1795185 Q58F21 Bromodomain testis-specific protein 80.85% 89.76%
CHEMBL4625 Q07817 Apoptosis regulator Bcl-X 80.48% 99.77%
CHEMBL3430907 Q96GD4 Aurora kinase B/Inner centromere protein 80.29% 97.50%
CHEMBL332 P03956 Matrix metalloproteinase-1 80.11% 94.50%
CHEMBL4187 Q99250 Sodium channel protein type II alpha subunit 80.07% 95.50%

Plants that contains it

Top
Below are displayed all the plants proven (via scientific papers) to contain this compound!
To see more specific details click the taxa you are interested in.
There are no matching plants.

Cross-Links

Top
PubChem 24769968
LOTUS LTS0206576
wikiData Q105137155